abstract：:Myocardial pH has been shown in animal models to be a sensitive indicator of ischemia. In vivo measurement in humans using 31p magnetic resonance spectroscopy is complicated by the overlap of blood 2,3-diphosphoglycerate peaks with the P(i) peak used for pH measurement. A "saturation transfer" method combined with spa...

journal_title：Magnetic resonance in medicine

authors： Blamire AM,Rajagopalan B,Radda GK

更新日期：1999-01-01 00:00:00

abstract：:For perfusion-based functional magnetic resonance imaging, the previously introduced flow-sensitive alternating inversion recovery (FAIR) technique is combined with single-shot RARE (rapid acquisition with relaxation enhancement) and GRASE (gradient and spin echo) imaging sequences. The advantages of these sequences c...

journal_title：Magnetic resonance in medicine

authors： Crelier GR,Hoge RD,Munger P,Pike GB

更新日期：1999-01-01 00:00:00

abstract：:1H transverse nuclear magnetic relaxation times (T2) and self-diffusion coefficients (SDCs) of water were measured in isolated proteoglycan aggregates from pig articular cartilage. The influence of varying osmotic pressure, as well as of different calcium concentrations, on the samples was investigated. Due to a struc...

journal_title：Magnetic resonance in medicine

authors： Werner A,Gründer W

更新日期：1999-01-01 00:00:00

abstract：:An automatic fMRI protocol for the investigation of the human auditory cortex has been developed. For the activation of the auditory system, the scanner noise itself is the source of sound. Rapid switching of B0 gradients allows the generation of tones of defined frequencies and amplitude on a conventional scanner wit...

journal_title：Magnetic resonance in medicine

authors： Bilecen D,Radü EW,Scheffler K

更新日期：1998-12-01 00:00:00

abstract：:Acute normovolemic hemodilution (HD) was induced in anesthetized rats to assess the effect of changes in hematocrit (Hct) on signal intensity in T2*-weighted magnetic resonance (MR) images. Other relevant physiological parameters were maintained invariant. Two degrees of HD were induced: mild (Hct reduced from 42.6+/-...

journal_title：Magnetic resonance in medicine

authors： Lin W,Paczynski RP,Celik A,Hsu CY,Powers WJ

更新日期：1998-12-01 00:00:00

abstract：:Half k-space gradient-recalled echo-planar imaging (GR-EPI) is discussed in detail. T2* decay during full k-space GR-EPI gives rise to unequal weighting of the lines of k-space, loss of signal intensity at the center of k-space, and a point-spread function that limits resolution. In addition, the long readout time for...

journal_title：Magnetic resonance in medicine

authors： Jesmanowicz A,Bandettini PA,Hyde JS

更新日期：1998-11-01 00:00:00

abstract：:The intra-individual and inter-individual variations of the global N-acetylaspartate (NAA) concentration were measured in a cohort of five 42+/-5 year-old normal females. The total NAA signal from the whole head was obtained with non-localized non-echo proton spectroscopy (1H-MRS) and converted into absolute mole amou...

journal_title：Magnetic resonance in medicine

authors： Gonen O,Viswanathan AK,Catalaa I,Babb J,Udupa J,Grossman RI

更新日期：1998-11-01 00:00:00

abstract：:In vivo lactate detection using gradient enhanced double quantum coherence transfer (DQCT) was significantly improved by addition of short-time-inversion-recovery (STIR). Phantom studies demonstrated lipid suppression down to the background noise level with 33% loss of lactate signal. In vivo studies using a rabbit mo...

journal_title：Magnetic resonance in medicine

authors： Nakai T,Rhine WD,Okada T,Stevenson DK,Spielman DM

更新日期：1998-10-01 00:00:00

abstract：:To quantify the extraction fraction, E, for gadopentetate across tumor capillaries, R3230 adenocarcinomas were implanted in the mammary fat pads of seven rats. The value of E was determined by using a two-compartment tissue model in which the endothelial transfer coefficient, K(PS) (ml x min(-1) x cc(-1) of tissue), w...

journal_title：Magnetic resonance in medicine

authors： Daldrup HE,Shames DM,Husseini W,Wendland MF,Okuhata Y,Brasch RC

更新日期：1998-10-01 00:00:00

abstract：:Certain kinds of artifacts have been reported when projection reconstruction (PR) techniques are used in magnetic resonance imaging (MRI). These will occur if the spacing between samples in k-space is too large. It has been suggested that PR requires finer k-space sampling than does two-dimensional Fourier reconstruct...

journal_title：Magnetic resonance in medicine

authors： Joseph PM

更新日期：1998-09-01 00:00:00

abstract：:Magnetic field homogeneity is of major concern for in vivo spectroscopy, and with the increased use of volumetric chemical shift imaging (CSI) techniques, the ability to shim over a large volume of tissue is now one of the primary limiting constraints in performing these studies. In vivo shimming is routinely performe...

journal_title：Magnetic resonance in medicine

authors： Spielman DM,Adalsteinsson E,Lim KO

更新日期：1998-09-01 00:00:00

abstract：:Proton-electron double-resonance imaging (PEDRI) was used to assess renal function by monitoring the flow of the exogenous nitroxide free radical proxyl carboxylic acid (PCA) through normal and injured kidneys in the living rat. Kidney damage was induced by treatment with 2-bromoethylamine (BEA), which provides a well...

journal_title：Magnetic resonance in medicine

authors： Seimenis I,Foster MA,Lurie DJ,Hutchison JM,Whiting PH,Payne S

更新日期：1998-08-01 00:00:00

abstract：:Fast proton magnetic resonance spectroscopic imaging (MRSI) using a multi-element head-coil array is examined with respect to three aspects: the coil design, the use of an appropriate signal combination method, and the design of the MRSI pulse sequence itself. An eight-element head-coil array has been developed to inc...

journal_title：Magnetic resonance in medicine

authors： Schäffter T,Börnert P,Leussler C,Carlsen IC,Leibfritz D

更新日期：1998-08-01 00:00:00

abstract：:The acquisition of complete three-dimensional (3D), segmented gradient-echo data sets to visualize the coronary arteries can be both time consuming and sensitive to motion, even with use of multiple breath-holding or respiratory gating. An alternate hybrid approach is demonstrated here, in which real-time interactive ...

journal_title：Magnetic resonance in medicine

authors： Hardy CJ,Darrow RD,Pauly JM,Kerr AB,Dumoulin CL,Hu BS,Martin KM

更新日期：1998-07-01 00:00:00

abstract：:It is shown that the effect of pH changes can be measured in proton NMR spectra through the pH sensitivity of the signal intensities of metabolite protons exchanging with water. To observe this phenomenon, pulse sequences must be used that can sensitively observe these exchangeable protons under physiological conditio...

journal_title：Magnetic resonance in medicine

authors： Mori S,Eleff SM,Pilatus U,Mori N,van Zijl PC

更新日期：1998-07-01 00:00:00

abstract：:Quantitative cerebral tissue volumes may be useful for an objective assessment of pathological changes in brain. Accurate determination of tissue volumes is complicated, however, by the partial volume averaging (PVA) effect. We have, therefore, developed a new pulse sequence that minimizes the PVA through the use of i...

journal_title：Magnetic resonance in medicine

authors： Bedell BJ,Narayana PA

更新日期：1998-06-01 00:00:00

abstract：:Pattern recognition techniques (factor analysis and neural networks) were used to investigate and classify human brain tumors based on the 1H NMR spectra of chemically extracted biopsies (n = 118). After removing information from lactate (because of variable ischemia times), unsupervised learning suggested that the sp...

journal_title：Magnetic resonance in medicine

authors： Maxwell RJ,Martínez-Pérez I,Cerdán S,Cabañas ME,Arús C,Moreno A,Capdevila A,Ferrer E,Bartomeus F,Aparicio A,Conesa G,Roda JM,Carceller F,Pascual JM,Howells SL,Mazucco R,Griffiths JR

更新日期：1998-06-01 00:00:00

abstract：:Recovery of the cerebral cortex after 10 min of cardiac arrest was studied in rat using noninvasive MRI techniques. The apparent diffusion coefficient (ADC) of brain water was imaged to document reversal of the metabolic impairment. Perfusion-weighted imaging and blood oxygen level dependent (BOLD) imaging were perfor...

journal_title：Magnetic resonance in medicine

authors： Schmitz B,Bock C,Hoehn-Berlage M,Kerskens CM,Böttiger BW,Hossmann KA

更新日期：1998-05-01 00:00:00

abstract：:In the pulsed arterial spin labeling (ASL) techniques EPISTAR, PICORE, and FAIR, subtraction of two images in which inflowing blood is first tagged and then not tagged yields a qualitative map of perfusion. An important reason this map is not quantitative is that there is a spatially varying delay in the transit of bl...

journal_title：Magnetic resonance in medicine

authors： Wong EC,Buxton RB,Frank LR

更新日期：1998-05-01 00:00:00

abstract：:A novel tagging method is introduced that increases the spatial resolution of estimates of myocardial radial thickening. The separation of adjacent parallel tag planes is customized to match the expected motion of specific regions of the heart wall. In regions in which the tags increase their separation over systole (...

journal_title：Magnetic resonance in medicine

authors： McVeigh ER,Bolster BD Jr

更新日期：1998-04-01 00:00:00

abstract：:This paper describes a technique for characterizing the gradient subsystem of a magnetic resonance (MR) system. The technique uses a Fourier-transform analysis to directly measure the k-space trajectory produced by an arbitrary gradient waveform. In addition, the method can be easily extended to multiple dimensions an...

journal_title：Magnetic resonance in medicine

authors： Alley MT,Glover GH,Pelc NJ

更新日期：1998-04-01 00:00:00

abstract：:Longitudinal and transverse relaxation rates for the 11B resonances in sodium borocaptate (BSH) at varying concentrations were measured in undiluted horse serum in a 4.7 Tesla field. The results could be fit by a model that assumes fast exchange of the BSH molecule between a free and a bound state, using values of 0.7...

journal_title：Magnetic resonance in medicine

authors： Bendel P,Frantz A,Zilberstein J,Kabalka GW,Salomon Y

更新日期：1998-03-01 00:00:00

abstract：:The purpose of the study was to test a newly developed, MR-compatible, liquid nitrogen-cooled cryoprobe. The probe has an outer diameter of 3.5 mm and was specifically developed for percutaneous, MR-guided, interstitial cryotherapy. The probe was inserted percutaneously into the livers of 10 rabbits. The cryotherapy p...

journal_title：Magnetic resonance in medicine

authors： Tacke J,Adam G,Speetzen R,Brucksch K,Bücker A,Heshel I,Prescher A,van Vaals JJ,Hunter DW,Rau G,Günther RW

更新日期：1998-03-01 00:00:00

abstract：:MR acoustic, or sound, noise due to gradient pulsing has been one of the problems in MRI, both in patient scanning as well as in many areas of psychiatric and neuroscience research, such as brain fMRI. Especially in brain fMRI, sound noise is one of the serious noise sources that obscures the small signals obtainable ...

journal_title：Magnetic resonance in medicine

authors： Cho ZH,Chung SC,Lim DW,Wong EK

更新日期：1998-02-01 00:00:00

abstract：:A gradient coil design algorithm capable of controlling the position of the homogeneous region of interest (ROI) with respect to the current-carrying wires is required for many advanced imaging and spectroscopy applications. A modified minimum inductance target field method that allows the placement of a set of constr...

journal_title：Magnetic resonance in medicine

authors： Chronik BA,Rutt BK

更新日期：1998-02-01 00:00:00

abstract：:Accumulation of lipids in atherosclerotic plaques causes progressive narrowing of the arterial lumen, often followed by thrombosis and ischemia. Currently several different methods, most requiring disruption of the plaque, are used to study the physical properties of lipids accumulated in plaques, and lipid compositio...

journal_title：Magnetic resonance in medicine

authors： Guo W,Morrisett JD,Lawrie GM,DeBakey ME,Hamilton JA

更新日期：1998-02-01 00:00:00

abstract：:To understand whether the NO-dependent vasodilator L-arginine was effective upon a chronically hypertensive cerebral capillary endothelium, dynamic susceptibility contrast MRI was used to measure the relative cerebral blood volume (rCBV) changes in nonischemic spontaneously hypertensive rats (SHRs). rCBV was measured ...

journal_title：Magnetic resonance in medicine

authors： Caramia F,Yoshida T,Hamberg LM,Huang Z,Hunter G,Wanke I,Zaharchuk G,Moskowitz MA,Rosen BR

更新日期：1998-01-01 00:00:00

abstract：:A technique using hyperpolarized (HP) 3He to image the small airways of the lung by using moderate flip angles and a short scanning period during early inspiration is demonstrated. Flip angles (alpha) ranging from 10-90 degrees were used in guinea pig experiments with scanning during the entire inspiration period. A s...

journal_title：Magnetic resonance in medicine

authors： Chen XJ,Chawla MS,Hedlund LW,Möller HE,MacFall JR,Johnson GA

更新日期：1998-01-01 00:00:00

abstract：:The goal of this work was to develop and evaluate a numerically optimized inversion pulse to be used with a homonuclear editing sequence to measure human cerebral GABA in vivo at 4.1 T in the occipital lobe. The optimized pulse was constructed using pallindromic symmetry with 30 pulses and 29 delays. The optimized pul...

journal_title：Magnetic resonance in medicine

authors： Hetherington HP,Newcomer BR,Pan JW

更新日期：1998-01-01 00:00:00

abstract：:K1 (first-order transfer constant from arterial plasma to myocardium for Gd-DTPA) and Vd (distribution volume of Gd-DTPA in myocardium) were measured in vivo in a canine model (n = 5) using MRI-derived myocardial perfusion curves and a compartmental model. Perfusion curves were obtained after a bolus injection of Gd-D...

journal_title：Magnetic resonance in medicine

authors： Vallée JP,Sostman HD,MacFall JR,Wheeler T,Hedlund LW,Spritzer CE,Coleman RE

更新日期：1997-12-01 00:00:00

abstract：:In this work, substrate selection was monitored in the left ventricle of the canine myocardium by following pyruvate and lactate oxidation under in vivo conditions at basal and elevated workloads. These studies were conducted in the open chest model using dynamic 13C NMR techniques in the presence and absence of dichl...

journal_title：Magnetic resonance in medicine

authors： Rath DP,Zhu H,Tong X,Jiang Z,Hamlin RL,Robitaille PM

更新日期：1997-12-01 00:00:00

abstract：:Quantitative artificial neural network analysis for 1550 ex vivo 31P nuclear magnetic resonance spectra from hypothermically reperfused pig livers was assessed. These spectra show wide ranges of metabolite concentrations and have been analyzed using metabolite prior knowledge based lineshape fitting analysis which had...

journal_title：Magnetic resonance in medicine

authors： Ala-Korpela M,Changani KK,Hiltunen Y,Bell JD,Fuller BJ,Bryant DJ,Taylor-Robinson SD,Davidson BR

更新日期：1997-11-01 00:00:00

abstract：:MR oximetry requires a T2 measurement that is accurate within 5% in vivo. Simple methods are susceptible to signal loss and tend to underestimate T2. Current methods utilize RF pulses or RF cycling patterns that prevent signal loss at each data acquisition. However, using these methods with imperfect pulses, T2 tends ...

journal_title：Magnetic resonance in medicine

authors： Foltz WD,Stainsby JA,Wright GA

更新日期：1997-11-01 00:00:00

abstract：:Applications of fMRI in functional brain imaging are mainly confined to single subject designs, prohibiting the assessment of subject or group by condition interactions (i.e., differential activations) or areas of conjoint activation. In this paper a framework for fMRI group designs, using statistical parametric mappi...

journal_title：Magnetic resonance in medicine

authors： Büchel C,Turner R,Friston K

更新日期：1997-11-01 00:00:00

abstract：:To date, most functional imaging centers have relied on ultrafast imaging approaches such as echo-planar imaging (EPI) techniques for acquiring functional brain activation data. These methods require specialized hardware and are not yet installed widely on clinical MR imagers, thus limiting the application of function...

journal_title：Magnetic resonance in medicine

authors： Constable RT

更新日期：1997-10-01 00:00:00

abstract：:Reduction of image-to-image signal fluctuations and imaging artifacts is important for fMRI studies. The imaging artifacts caused by respiration, cardiac pulsation, and gross head motion and the suppression of these artifacts have been studied for many years. However, the artifacts caused by eye movement and their eff...

journal_title：Magnetic resonance in medicine

authors： Chen W,Zhu XH

更新日期：1997-10-01 00:00:00

abstract：:The apparent diffusion coefficient (ADC) in the optic nerve was measured from diffusion-weighted magnetic resonance imaging using an intravoxel incoherent motion (IVIM) sequence. The subjects were seven normal volunteers and eight patients with multiple sclerosis (MS) with a total of four optic nerves with acute neuri...

journal_title：Magnetic resonance in medicine

authors： Iwasawa T,Matoba H,Ogi A,Kurihara H,Saito K,Yoshida T,Matsubara S,Nozaki A

更新日期：1997-09-01 00:00:00

abstract：:The recently developed technique of gradient, high-resolution magic-angle spinning NMR (g-hr-MAS-NMR) spectroscopy was applied to the study of ex vivo human lipoma and liposarcoma tissue. Compared with conventional 1H-NMR, the g-hr-MAS method yielded a large improvement in spectral resolution and permitted the detecti...

journal_title：Magnetic resonance in medicine

authors： Millis KK,Maas WE,Cory DG,Singer S

更新日期：1997-09-01 00:00:00

abstract：:A modified Prony method (MPM) was applied to analyze the main signals present in spatially resolved 31P NMR spectra of MCF7 breast tumors implanted in nude mice. First, the method was tested on synthetic data to establish its limits of reliability. Its performance with respect to peak identification and quantification...

journal_title：Magnetic resonance in medicine

authors： Viti V,Ragona R,Guidoni L,Barone P,Furman E,Degani H

更新日期：1997-08-01 00:00:00

abstract：:MR imaging experiments were conducted to investigate the feasibility of estimating vascular pulse pressure waveforms from measurements of blood flow rates and vessel cross-sectional area. Blood flow waveforms were measured in the aorta's of three 25-30-kg pigs at multiple imaging sections using phase-contrast velocity...

journal_title：Magnetic resonance in medicine

authors： Urchuk SN,Fremes SE,Plewes DB

更新日期：1997-08-01 00:00:00